Preview

Patient-Oriented Medicine and Pharmacy

Advanced search

Features of damage to the nervous system in herpesvirus infections

https://doi.org/10.37489/2949-1924-0021

Abstract

Actuality. Herpesvirus diseases are characterized by a wide distribution, polymorphism of clinical manifestations and severity of the course up to the development of lethal outcomes. The purpose of the study: to identify the features of the damage to the nervous system in herpes infections in modern conditions. Materials and methods. Under observation there were 60 patients with lesions of the nervous system due to herpesvirus infections, hospitalized in the Infectious Clinical Hospital in 2015-2021. Results and discussion. The analysis of the main clinical and laboratory parameters was carried out and the features of the damage to the nervous system in herpesvirus infections were established. Conclusion. The results of the study showed that patients with VZV infection prevailed among all patients — 78.3%. The range of lesions of the nervous system was presented in the form of serous meningitis (48.3%), meningoencephalitis (43.3%), encephalitis (8.4%).

About the Authors

S. N. Eshmolov
Yaroslavl State Medical University
Russian Federation

Sergey N. Eshmolov — Candidate of Medical Sciences, Assistant, Department of Infectious Diseases, Epidemiology and Children's Infections

Author ID: 687193

Yaroslavl


Competing Interests:

The authors declare no conflict of interest



E. G. Klimovitskaya
Yaroslavl State Medical University
Russian Federation

Elizaveta G. Klimovitskaya — Candidate of Medical Sciences, Associate Professor, Department of Infectious Diseases

Author ID: 898517

Yaroslavl


Competing Interests:

The authors declare no conflict of interest



M. N. Kuzmina
Yaroslavl State Medical University
Russian Federation

Maria N. Kuzmina — Candidate of Medical Sciences, Associate Professor, Department of Hospital Surgery

Author ID: 1053509

Yaroslavl


Competing Interests:

The authors declare no conflict of interest



I. G. Sitnikov
Yaroslavl State Medical University
Russian Federation

Ivan G. Sitnikov — Doctor of Medical Sciences, Prof., Head of the Department of Infectious Diseases, Epidemiology and Children's Infections

Author ID: 493735

Yaroslavl


Competing Interests:

The authors declare no conflict of interest



References

1. Скрипченко Н.В., Лобзин Ю.В., Иванова Г.П., Команцев В.Н., Алексеева Л.А., Иванова М.В., Вильниц А.А., Горелик Е.Ю., Скрипченко Е.Ю. Нейроинфекции у детей. Детские инфекции. 2014;13(1):8-18. https://doi.org/10.22627/2072-8107-2014-13-1-8-18 [Skripchenko N.V., Lobzin V.V., Ivanova G.P., Komantsev V.N., Alekseeva L.A., Ivanova M.V., Vilnits A.A., Gorelik E.Yu., Skripchenko E.Yu. Neuroinfectious diseases in children.Children infections. 2014;13(1):8-18. (In Russ.) https://doi.org/10.22627/2072-8107-2014-13-1-8-18]

2. Кимирилова О.Г., Харченко Г.А., Галимзянов Х.М., Башкина О.А. Вирусные нейроинфекции у детей. Астраханский медицинский журнал. 2016;11(2):33–42. [Kimirilova O.G., Kharchenko G.A., Galimzyanov Kh.M., Bashkina O.A. Viral neuroinfections in children. Astrakhan medical journal. 2016;11(2):33–42. (In Russ.)]

3. Белялетдинова И.Х., Малинникова Е.Ю., Митрофанова И.В., Прыткова М.И. Поражения нервной системы, вызванные вирусом Варицелла-Зостер у детей. Детские инфекции. 2016;15(3):10–15. [Belyaletdinova I.Kh., Malinnikova E.Yu., Mitrofanova I.V., Prytkova M.I. Nervous system lesions caused by the Varicella-Zoster virus in children. Children's infections. 2016;15(3):10–15. (In Russ.)]

4. Самсыгина Г.А. Герпес-вирусные инфекции у детей. Consilium Medicum. Педиатрия (Прил.). 2016; 2: 18–23. [Samsygina G.A. Herpes virus infections in children. Consilium Medicum. Pediatrics (Suppl.). 2016; 2: 18–23. (In Russ.)]

5. Матвеева Т.В., Якупов Э.З., Хафизова И.Ф., Хакимова А.Р., Муллаянова Р.Ф., Халитова Л.А. Трудности и ошибки в диагностике герпесвирусных нейроинфекций. Вестник современной клинической медицины. 2013;6(3):36–39. [Matveeva T.V., Yakupov E.Z., Khafizova I.F., Khakimova A.R., Mullayanova R.F., Khalitova L.A. Difficulties and errors in the diagnosis of herpesvirus neuroinfections. Bulletin of modern clinical medicine. 2013;6(3):36–39. (In Russ.)]

6. Скрипченко Е.Ю., Иванова Г.П., Скрипченко Н.В., Мурина Е.А., Карев В.Е. Клинико-этиологические особенности энцефалитов у детей раннего и старшего возраста. Практическая медицина. 2018;16(8):11–20.DOI: 10.32000/2072-1757-2018-8-11-20 [Skripchenko E.Yu., Ivanova G.P., Skripchenko N.V., Murina E.A., Karev V.E. Clinical and etiological features of encephalitis in young and elderly children. Practical Medicine. 2018;16(8):11-20. (In Russ.)]

7. Крамарь Л.В., Бокова З.М., Мыльникова М.М., Торшхоева Л.А. Ветряночный энцефалит у детей: клинико-лабораторные характеристики. Волгоградский научно-медицинский журнал. 2019;1:42–45. [Kramar L.V., Bokova Z.M., Mylnikova M.M., Torshkhoeva L.A. Chickenpox encephalitis in children: clinical and laboratory characteristics. Volgograd Scientific Medical Journal. 2019;1:42–45.(In Russ.)]

8. Скрипченко Н.В., Иванова Г.П., Пальчик А.Б., Скрипченко Е.Ю., Лобзин Ю.В., Мурина Е.А. Неврологические осложнения и прогноз их развития при ветряной оспе у детей. Педиатрия им. Г.Н. Сперанского. 2016; 95(2):14-21. [Skripchenko N.V., Ivanova G.P., Palchik A.B., Skripchenko E.Yu., Lobzin Yu.V., Murina E.A. Neurological complications and prognosis of their development after varicella in children. Pediatrian.a. G.N. Speransky. 2016;95(2):14-21. (In Russ.)]

9. Рюмин А.М., Собчак Д.М., Отмахова И.А., Сабурова О.А. Неврологические проявления реактивации вируса опоясывающего герпеса. Журнал инфектологии. 2022;14(1):31-42. https://doi.org/10.22625/2072-6732-2022-14-1-31-42 [Ryumin A.M., Sobchak D.M., Otmakhova I.A., Saburova O.A. Neurological manifistations of herpes zoster virus reactivation. Journal Infectology. 2022;14(1):31-42. (In Russ.)]

10. Кокорева С.П., Макарова А.В., Романцов Г.П., Колесникова Н.Д. Случай острого энцефалита цитомегаловирусной этиологии. Лечение и профилактика. 2020;10(3):79–81. [Kokoreva S.P., Makarova A.V., Romantsov G.P., Kolesnikova N.D. A case of a cuteen cephalitis of cytomegalovirus etiology. Treatment and prevention. 2020;10(3):79–81. (In Russ.)]

11. Симонова Е.В., Харламова Ф.С., Учайкин В.Ф., Дроздова И.М., Егорова Н.Ю. Поражение ЦНС при герпесвирусной моно- и микст-инфекции 6-го типа у детей. Педиатрия им. Г.Н. Сперанского. 2016;95(2):22–29. [Simonova E.V., Kharlamova F.S., Uchaikin V.F., Drozdova I.M., Egorova N.Yu. Damage to the central nervous system in herpes virus mono- and mixed infection of the 6th type in children. Pediatrics n.a. G.N. Speransky. 2016;95(2):22–29. (In Russ.)]

12. Пятикова М.В., Кравченко Л.В., Левкович М.А. Клиническая характеристика герпетической инфекции 6 типа у детей. Фундаментальные исследования. 2015;1–2:342–345. [Pyatikova M.V., Kravchenko L.V., Levkovich M.A. Clinical characteristics of herpes infection type 6 in children. Fundamental Research. 2015;1–2:342–345. (In Russ.)]


Review

For citations:


Eshmolov S.N., Klimovitskaya E.G., Kuzmina M.N., Sitnikov I.G. Features of damage to the nervous system in herpesvirus infections. Patient-Oriented Medicine and Pharmacy. 2023;1(3):25-31. (In Russ.) https://doi.org/10.37489/2949-1924-0021

Views: 292


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2949-1924 (Online)

Адрес редакции и издательства:

ООО «Издательство ОКИ»
115522, Москва, Москворечье ул., 4-5-129

Генеральный директор Афанасьева Елена Владимировна

Тел. + 7 (916) 986-04-65; Email: eva88@list.ru