Risk prediction for the thrombosis of permanent vascular access
https://doi.org/10.37489/2949-1924-0020
Abstract
Aim: to improve surgical treatment results in patients with primary permanent vascular access. Materials and methods: the results of the treatment of 168 patients with native arteriovenous radiocephalic fistula were analyzed. The results of treatment within 1 year were tracked According to the observation results, patients were divided into 2 groups: the 1st group — patients who did not develop thrombosis of an arteriovenous fistula for 1 year of hemodialysis, and the 2nd group — patients who had vascular access due to thrombosis during the first year. Results: the factors with the greatest degree of influence on the risk of thrombosis during time periods up to 6 months and from 6 months to 1 year were identified. However, not all of them by their characteristics, satisfied the conditions for constructing a multidimensional logistic regression and a predictive model based on it. On the basis of the identified factors, prognostic models have been established that assess the risk of thrombosis of permanent vascular access at time intervals of up to 6 months and from 6 months to 1 year. Conclusion: the formation of a predictive model considering a variety of factors can give an answer to the risk of thrombosis formation and determine ways to reduce it.
About the Authors
I. N. StaroverovRussian Federation
Ilia N. Staroverov — MD, D.Sc. (Medicine), head of the vascular surgery department, head of the department of surgery of the institute of postgraduate education
Author ID: 717973
Yaroslavl
Competing Interests:
The authors declare no conflict of interest
N. S. Noshchenko
Russian Federation
Nikita S. Noshchenko — MD, PhD, Assistant of the department of surgery of the institute of postgraduate education
Author ID: 1015260
Yaroslavl
Competing Interests:
The authors declare no conflict of interest
L. B. Shubin
Russian Federation
Leonid B. Shubin — PhD, Associate Professor of the department of pathological anatomy
Author ID: 484053
Yaroslavl
Competing Interests:
The authors declare no conflict of interest
O. M. Lonchakova
Russian Federation
Oksana M. Lonchakova — MD, PhD, Associate Professor of the department of surgery of the institute of postgraduate education
Author ID: 915633
Yaroslavl
Competing Interests:
The authors declare no conflict of interest
References
1. Томилина Н.А., Андрусев А.М., Перегудова Н.Г., Шинкарев М.Б. Заместительная терапия терминальной хронической почечной недостаточности в Российской Федерации в 2010-2015 гг. Отчет по данным Общероссийского Регистра заместительной почечной терапии Российского диализного общества, Часть первая. Нефрология и диализ. 2017. 19(4):1-95. doi: 10.28996/1680-4422-2017-4suppl-1-95 [Tomilina N.A., Andrusev A.M., Peregudova N.G., Shinkarev M.B. Renal replacement therapy for End Stage Renal Disease in Russian Federation, 2010-2015. Russian National Renal Replacement Therapy Registry Report of Russian Public Organization of Nephrologists "Russian Dialysis Society", Part 1. Nephrology and dialysis. 2017. 19(4):1-95. doi: 10.28996/1680-4422-2017-4suppl-1-95]
2. Стецюк Е.А. Основы гемодиализа. ГЭОТАР–МЕД. – М. : Изд–во ГЭОТАР–МЕД, 2001. – 392с. [Stecyuk E.A. Osnovy gemodializa. GEHOTAR–MED. – M. : Izd–vo GEHOTAR–MED, 2001. – 392s.]
3. Smith GE, Barnes R, Fagan M, Chetter IC. The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes. Ann Vasc Surg. 2016 Apr;32:9-14. doi: 10.1016/j.avsg.2015.11.002. Epub 2016 Jan 25. PMID: 26820359.
4. Yeh CH, Huang TS, Wang YC, Huang PF, Huang TY, Chen TP, Yin SY, Yu YW. Effects of Antiplatelet Medication on Arteriovenous Fistula Patency After Surgical Thrombectomy. Curr Vasc Pharmacol. 2016;14(4):353-9. doi: 10.2174/1570161114666160229115844. PMID: 26924326.
5. Tanner NC, Da Silva A. Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts. Cochrane Database of Systematic Reviews. 2015, Issue 7. Art. No.: CD002786. DOI: 10.1002/14651858.CD002786.pub3. Accessed 22 August 2023.
6. King DH, Paulson WD, Al-Qaisi M, Taylor MG, Panayiotopoulos Y, Abeygunarsekara S, Chan A, Ali G, Chemla ES. Volume blood flow, static pressure ratio and venous conductance in native arterio-venous fistulae: three surveillance methods compared. J Vasc Access. 2015 May-Jun;16(3):211-7. doi: 10.5301/jva.5000324. Epub 2015 Jan 30. PMID: 25656259.
7. Morton SK, Rodríguez AJ, Morris DR, Bhandari AP, Moxon JV, Golledge J. A Systematic Review and Meta-Analysis of Circulating Biomarkers Associated with Failure of Arteriovenous Fistulae for Haemodialysis. PLoS One. 2016 Jul 26;11(7):e0159963. doi: 10.1371/journal.pone.0159963. PMID: 27458819; PMCID: PMC4961283.
8. Реброва О.Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ STATISTICA – М.: Медиасфера, – 2002, – 312 с. [Rebrova O.YU. Statisticheskij analiz meditsinskikh dannykh. Primenenie paketa prikladnykh programm STATISTICA – Moscow: Mediasfera, – 2002, – 312 s. (In Russ).]
9. Robert H. Fletcher, Suzanne W. Fletcher, Edward Harris Wagner. Clinical Epidemiology: The Essentials. Williams & Wilkins, 1996. – 352s
10. Плещёв И. Е., Николенко В. Н., Ачкасов Е. Е., Шкребко А. Н. Алгоритм применения индивидуально — группового протокола при комплексной реабилитации пациентов с саркопенией. Вестник «Биомедицина и Социология». 2022;24(5):44-53. doi:10.26787/nydha-2618-8783-2022-7-2-44-53.
11. Румянцев П.О., Саенко В.А., Румянцева У.В., Чекин С.Ю. Статистические методы анализа в клинической практике. ГУ-Медицинский радиологический научный центр РАМН, г. Обнинск. 2009. – 44 с. [Rumyancev P.O., Saenko V.A., Rumyanceva U.V., Chekin S.Yu. Statisticheskie metody analiza v klinicheskoy praktike. GU-Medicinskiy radiologicheskiy nauchnyy centr RAMN, g. Obninsk. 2009. – 44 s.]
Review
For citations:
Staroverov I.N., Noshchenko N.S., Shubin L.B., Lonchakova O.M. Risk prediction for the thrombosis of permanent vascular access. Patient-Oriented Medicine and Pharmacy. 2023;1(3):15-24. (In Russ.) https://doi.org/10.37489/2949-1924-0020