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Changes in the quantitative composition of free testosterone in the blood serum of participants in military operations and its effect on sexual activity

https://doi.org/10.37489/2949-1924-0066

EDN: QWUDPA

Abstract

Relevance. Participation in military operations involves a large number of human resources, usually young men. In most cases, this leads to post-traumatic stress disorder (PTSD). In the pathogenesis of this condition, great importance is given to changes in the hormonal background, which in turn contribute to changes in the production of sex hormones. However, despite the active discussion on this topic, many unresolved issues.

Objective. To study the effect of PTSD in participants of military operations on the level of free testosterone in the blood serum and the relationship with sexual activity

Materials and methods. The study involved 100 participants who agreed to participate in the survey. All subjects were divided into five groups, depending on the time since participation. The average duration of combat was 6–8 months. The studies were conducted on an outpatient basis. A study of the level of free testosterone level and the assessment of sexual activity were evaluated.

Results. The study revealed a certain discordance between the free testosterone levels in the blood serum of participants in military operations at different times compared with the stress factor received and sexual activity. This phenomenon was manifested by a decrease in sexual activity against the background of an increase in free testosterone in the blood serum. Perhaps this is due to several factors that should be considered in combination. Therefore, the first and main factor may be stress, which affects and activates the sympathoadrenal system, as confirmed in the literature.

Conclusions. In participants of military operations, against the background of an increase in the amount of free testosterone in the blood serum, there is a decrease in sexual activity, which gradually recovers with increasing time elapsed from the moment of stress.

About the Authors

V. V. Maslyakov
Saratov State Medical University named after V.I. Razumovsky ; Saratov Medical University "Reaviz"
Russian Federation

Vladimir V. Maslyakov — Dr. Sci. (Med.), Professor, Department of Mobilization Preparation of Healthcare and Disaster Medicine

Saratov


Competing Interests:

The authors declare no conflict of interest.



S. A. Sidelnikov
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

Sergey A. Sidelnikov — Dr. Sci. (Med.), Associate Professor, Colonel of the Reserve Medical Service, Head of the Department of Mobilization Preparation of Healthcare and Disaster Medicine

Saratov


Competing Interests:

The authors declare no conflict of interest.



A. E. Burekeshev
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

Alim E. Burekeshev — Department of Mobilization Preparation of Healthcare and Disaster Medicine

Saratov


Competing Interests:

The authors declare no conflict of interest.



Yu. V. Focht
Saratov Medical University "Reaviz"
Russian Federation

Yulia V. Focht — Department of Pharmacology and Pharmacy

Saratov


Competing Interests:

The authors declare no conflict of interest.



I. V. Romanova
Saratov Medical University "Reaviz" ; 428 Military Hospital of the Ministry of Defense
Russian Federation

Irina V. Romanova — Head of Department, Medical Methodologist

Saratov


Competing Interests:

The authors declare no conflict of interest.



References

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Review

For citations:


Maslyakov V.V., Sidelnikov S.A., Burekeshev A.E., Focht Yu.V., Romanova I.V. Changes in the quantitative composition of free testosterone in the blood serum of participants in military operations and its effect on sexual activity. Patient-Oriented Medicine and Pharmacy. 2024;2(4):39-44. (In Russ.) https://doi.org/10.37489/2949-1924-0066. EDN: QWUDPA

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ISSN 2949-1924 (Online)

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